View Full Version : No High Medical Marijuana
http://news.yahoo.com/s/theweek/20110405/cm_theweek/213884
New York – Scientists believe they can isolate the pain-easing benefits of medical marijuana — so sufferers can consume it without becoming foggy and paranoid
What is marijuana without the high? Still a very effective painkiller. And now, scientists believe they can harness the drug's anaesthetic action while doing away with its psychedelic effects. In a new paper published in the journal Nature Chemical Biology, Professor Li Zhang and a team of scientists at the U.S. National Institute on Alcohol Abuse and Alcoholism report that THC can potentially be used as a side-effect-free painkiller. Is a new class of "non-psychotropic cannabinoids" on the way? Here's a brief guide:
What is this breakthrough exactly?
Zhang and his team discovered that tetrahydrocannabinol (more commonly known as THC), the main psychoactive ingredient in cannabis, produces different effects by bonding to different receptors in the brain. Scientists have known for years that THC bonds with a certain receptor to produce the classic disorienting marijuana high. But now researchers have identified precisely where THC targets the nervous system to lessen anxiety and dull pain. Hence, the potential to satisfy medical marijuana's desire for pure pain relief.
How'd they figure this out?
By experimenting on mice, naturally. Scientists blocked the pain-reducing receptors in the stoned rodents' brains, then subjected them to a "tail-flick test" — hitting mices' tails with "focused heat" — and counted how long it took for them to respond. The fact that the mice still felt pain, even when they were dosed with THC, "confirms that the drug's pain-relief and psychotropic effects can be decoupled," says Andy Coghlan at The New Scientist.
So... THC pain pills?
Quite possibly. "Soon," says Annalee Newitz at IO9, "people whose stomachs are too tender for aspirin or ibuprofin may be swallowing THC pills to get rid of headaches."
Could another result be THC pills that do nothing but get you high?
It's the question recreational users will be pondering: "Is there a way to create a synthetic form of THC that does nothing but get you high, without all those pesky 'medicinal' side-effects?" asks Newitz at IO9. Stay tuned.
So the big question is what some of you medical marijuana fans think of this? I think it's marvelous science and could get the the benefits of marijuana legal in all of the states if we no longer have the high associated with it.
Mr Lefty
04-08-2011, 07:48 AM
personally I don't think it was bad to begin with... it's a fear or stereotype from ages ago...
it's like taking the alcohol out of wine so now we can drink it solely for the antioxidants...
personally I don't think it was bad to begin with... it's a fear or stereotype from ages ago...
it's like taking the alcohol out of wine so now we can drink it solely for the antioxidants...
I don't either, I think we should be allowed to use it recreationally, but that is unlikely to happen. However, if this removes the stigmata from it and actually gets it's benefits to market with no issue. It's worth it.
Does it also provide some of the medical benefits of munchies? Especially ti chemor patients that cant keep food down?
Overall its a step in the right direction but its not perfect, I'm afraid there are still too many people who are scared of the evil weed to let it get out there.
Recreational weed is also something that should be legalized, but thats a different disscussion
Does it also provide some of the medical benefits of munchies? Especially ti chemor patients that cant keep food down?
Don't know, doesn't look like they studied if the rats had a craving for Doritos or not. lol
Don't know, doesn't look like they studied if the rats had a craving for Doritos or not. lol
Then wtf good is med weed if it doesnt have the nasty side effects of laziness, munchies, short term memory loss, impared coordination, giggles, closed eye-edness, and an unquestionable navigation ability towards the local 7-11.
Really who cares, its never gonna be as good as the real thing because for 50% of the customers out there they get headaches so they can get a perscription to the med weed, the other 50% would tell you how much pain they are in, but are too busy suffering from real pain.
askmrjesus
04-08-2011, 08:55 AM
The real question is, Why do fucking mice get all the good shit?
Asshole mice.
JC
The real question is, Why do fucking mice get all the good shit?
Asshole mice.
JC
hahahahhahahahhaahhahha
Homeslice
04-08-2011, 09:15 AM
because for 50% of the customers out there they get headaches so they can get a perscription to the med weed
Yep
I'd say this has the potential to become flat-out ownage.
Kaneman
04-08-2011, 10:12 AM
[QUOTE=Trip;462342]http://news.yahoo.com/s/theweek/20110405/cm_theweek/213884
So the big question is what some of you medical marijuana fans think of this? I think it's marvelous science and could get the the benefits of marijuana legal in all of the states if we no longer have the high associated with it.[/QUOTE
THC pill don't have cannabinoids, which are what fight cancer and tumors. They could be good for killing pain though I suppose.
I, of course, still think good ol' fashioned Cannabis is the way to go for Medicinal use.
Archren
04-08-2011, 10:15 AM
THC pill don't have cannabinoids, which are what fight cancer and tumors. They could be good for killing pain though I suppose.
I, of course, still think good ol' fashioned Cannabis is the way to go for Medicinal use.
Doctor's Orders.... :D
THC pill don't have cannabinoids, which are what fight cancer and tumors. They could be good for killing pain though I suppose.
I, of course, still think good ol' fashioned Cannabis is the way to go for Medicinal use.
Which would make sense for Cancer patients, but how many people wanting it are using it for cancer/tumors?
Kaneman
04-08-2011, 10:25 AM
Which would make sense for Cancer patients, but how many people wanting it are using it for cancer/tumors?
I've been hearing about THC pills for quite some time, and I agree they could be a very useful and far safer pain reliever, than say Tylenol.
What I'm afraid of is this sort of half legalization where the government (that has always maintained THC has NO medical benefits) says, "Hey, we gave you THC pills, now that's as good as its going to get." And then millions of people will miss out on the other benefits of the Cannabis plant, and innocents still go to prison, etc. etc.
There is much more to Cannabis than just the THC. I can definitely see where an effective THC pill could help sway public opinion on Cannabis though.
Yeah, but this also could be a stepping stone toward full legalization if we have a chance to go legalization. There is such a misconception in the general public about it, maybe if we get them use to the benefits without the high, they would be more tolerant of more uses for the drug.
Homeslice
04-08-2011, 10:38 AM
But since they're making such a big deal about removing the high, then to me it just reinforces the notion that high = bad and therefore recreational users are bad. So I doubt it will improve the odds of legalization.
Kaneman
04-08-2011, 10:39 AM
Yeah, but this also could be a stepping stone toward full legalization if we have a chance to go legalization. There is such a misconception in the general public about it, maybe if we get them use to the benefits without the high, they would be more tolerant of more uses for the drug.
If big pharma figures out a way to make profit off THC they're going to do everything in their power to keep people coming to the pharmacy and shelling out money to buy their product. Cannabis and growing cannabis will remain illegal, otherwise they won't be able to profit.
Unfortunately, I don't see it as a stepping stone, but rather a way to keep it illegal. Many of those screaming for legalization are doing so in the name of actual medical necessity. If a THC pill cures what ails them, they're less likely to be as passionate about legalization.
Avatard
04-08-2011, 02:20 PM
If it grows in your yard, and it's FREE, big pharma can't rape you.
They know this, they want your money. The government helps them, because they're in the pockets of big pharma.
There is no legitimate reason to make this harmless herb, used medicinally for CENTURIES, illegal in the 1st place.
They have had "marinol" pills for YEARS, and most people who took them in trials compared to smoking, found little or no relief.
Cannabis has many different strains, many different components, and while this research may help pain sufferers, there are MANY medicinal uses for this herb, as it has MANY wide-ranging effects, due to the MANY cannabinoids within it...NOT just THC.
My condition seems to benefit from the CBD component.
This is just another bullshit move to rob people of cheap herbal medicine, put money in big pharma pocketbooks, and keep people going to jail, in order to keep DEA agents, police, and courts employed persecuting, and kicking in families' doors, and killing their dogs, and children.
If it grows in your yard, and it's FREE, big pharma can't rape you.
They know this, they want your money. The government helps them, because they're in the pockets of big pharma.
There is no legitimate reason to make this harmless herb, used medicinally for CENTURIES, illegal in the 1st place.
They have had "marinol" pills for YEARS, and most people who took them in trials compared to smoking, found little or no relief.
Cannabis has many different strains, many different components, and while this research may help pain sufferers, there are MANY medicinal uses for this herb, as it has MANY wide-ranging effects, due to the MANY cannabinoids within it...NOT just THC.
My condition seems to benefit from the CBD component.
This is just another bullshit move to rob people of cheap herbal medicine, put money in big pharma pocketbooks, and keep people going to jail, in order to keep DEA agents, police, and courts employed persecuting, and kicking in families' doors, and killing their dogs, and children.
And you know what the majority public perception of you from this quote will be "just another stoner that doesn't really want the pain medicine, he wants the high."
You aren't going to get it legalized any time soon, but if a company makes in roads into getting benefits for pain sufferers, I don't see a disadvantage in that.
Avatard
04-08-2011, 02:42 PM
I don't think the general public is that naive anymore.
They know the kinda shit government does, and the absurdity of some of their propaganda is starting to look rather obvious anymore.
It's now known that prohibition of alcohol was actually government collusion with Rockefeller to curb Ethanol's use use in early cars (because farmers could make their own fuel from corn), like Henry Ford's Model T (that with different carbs ran on "Regular, or Ethyl"), and that cannabis suffered a similar fate at the hands of William Randolf Hearst to protect his paper interests, as hemp is over 4x more efficient at making paper.
Now that government is so glaringly obviously in the pocket of big pharma, I don't think people look at such ideas quite as suspiciously as you suggest.
No tinfoil hat is required, as these historic incidents of government collusion with robber barons is now common knowledge because of free exchange of information (read: Internet), as the standard press (read: Hearst) is no longer in control of all media.
I don't think the general public is that naive anymore.
They know the kinda shit government does, and the absurdity of some of their propaganda is starting to look rather obvious anymore.
It's now known that prohibition of alcohol was actually government collusion with Rockefeller to curb Ethanol's use use in early cars (because farmers could make their own fuel from corn), like Henry Ford's Model T (that with different carbs ran on "Regular, or Ethyl"), and that cannabis suffered a similar fate at the hands of Randolf Hearst to protect his paper interests, as hemp is over 4x more efficient at making paper.
Now that government is so glaringly obviously in the pocket of big pharma, I don't think people look at such ideas quite as suspiciously as you suggest.
I think you are crazy if you believe the general public isn't still as naive. Especially about pot. Jury duty on the drug case I worked was hilarious how naive the jury pool was.
Avatard
04-08-2011, 02:54 PM
Well, they have been telling the lie for over 80 years now, so that's almost a century of propaganda to overcome...but it's coming.
Kaneman
04-08-2011, 04:06 PM
Trip, Avatard is in complete denial about the severe lack of thinking and reasoning ability among the general population. You have to admire his hope for humanity though.
Avatard
04-08-2011, 04:22 PM
Nah dude, I never underestimate the stupidity of the general public...remember; I used to sell exotic Italian racing pocketbikes over the phone. Shit that would tear you a new asshole if you weighed 250 Lbs, and rode like Rossi...and every fucking day I'd have to talk to retards convinced that they needed the most powerful models I sold for their fucking 4-year-old, who didn't even know how to ride a bike yet.
I talked to more stupid people in the 6 years I was in the minimoto business than I thought ever existed, and it forever changed my opinion of just how stupid the general populace was (silly me, I was raised in the Northeast, among what I would later come to realize was a non-representative demographic). Did I feel smug, superior, privileged??
Nah, just lonely. Lonely, and sad for the fact that I knew in my heart that social change would only come at a glacial fucking pace in this country.
So far, the one-step-forward, two-steps-back shuffle has been worse than even I could have even predicted with that knowledge, however. Eight years of Bush set this joint back a good two decades, and homeboy has been a fine pet to the establishment, but hasn't delivered shit, really.
No, I get that this country is stupid. Over 80% still believe in the fucking Easter Bunny (Jesus), and only half believe in evolution. Trust me, I've traveled the world, and I have valid comparisons.
Still, the truth eventually ALWAYS comes out...no matter how stupid those being deceived really are. That's one thing about lies. They all have a shelf life.
In Brazil we say "a Lie has short legs"...
Off topic, I have always wanted to see a decent pocketbike. All the ones I have seen around here suck serious ass and one of them was Italian. It was a Blata. It got stomped by our CRF88s. The thing cost double ours too. Can't imagine what the good ones cost.
Archren
04-08-2011, 04:36 PM
In Brazil we say "a Lie has short legs"...
Mentira tem pernas curtas.. wow I haven't heard that in ages. :lol:
defector
04-08-2011, 05:09 PM
Off topic, I have always wanted to see a decent pocketbike. All the ones I have seen around here suck serious ass and one of them was Italian. It was a Blata. It got stomped by our CRF88s. The thing cost double ours too. Can't imagine what the good ones cost.
I still have a few. Mine are all Pasta powered (Polini) - I think Blata is Czech made. IMO, they are much harder to ride fast that any dirtbike of any size. On your cross country trip, hit me up when you are near AZ. I'll drive a couple of them up there for you and whoever is with you to ride.
VatorMan
04-08-2011, 05:54 PM
If it grows in your yard, and it's FREE, big pharma can't rape you.
They know this, they want your money. The government helps them, because they're in the pockets of big pharma.
There is no legitimate reason to make this harmless herb, used medicinally for CENTURIES, illegal in the 1st place.
They have had "marinol" pills for YEARS, and most people who took them in trials compared to smoking, found little or no relief.
Cannabis has many different strains, many different components, and while this research may help pain sufferers, there are MANY medicinal uses for this herb, as it has MANY wide-ranging effects, due to the MANY cannabinoids within it...NOT just THC.
My condition seems to benefit from the CBD component.
This is just another bullshit move to rob people of cheap herbal medicine, put money in big pharma pocketbooks, and keep people going to jail, in order to keep DEA agents, police, and courts employed persecuting, and kicking in families' doors, and killing their dogs, and children.
Oh, bullshit. I make beer. As long as I don't try and sell it, I can make up to 100 gallons a year. No Federals come by to check my house etc... Most people are lazy. They will let an authorized grower package it and buy it over the counter. Same principle.
Avatard
04-08-2011, 06:44 PM
Dude, you need a modicum of intelligence, a number of ingredients, time, patience, and considerable equipment to make beer.
Cannabis is a fucking weed. You don't need shit (although come to think of it, a bit of fertilizer wouldn't hurt).
If people would be allowed to grow it, many would, and big pharma would definitely take a hit (pun intended).
VatorMan
04-08-2011, 06:50 PM
You give people WAY to much credit. Think Jiffy Lube and Wal Mart.
Avatard
04-08-2011, 07:05 PM
Yep, but let's face it...many guys still do change their own oil, or else they wouldn't sell filters at the Pep Boys.
Sure, it's not that many, but I think it's you who are under-estimating.
What I think you're under-estimating is GREED.
Flexin
04-08-2011, 07:31 PM
Yeah, but this also could be a stepping stone toward full legalization if we have a chance to go legalization. There is such a misconception in the general public about it, maybe if we get them use to the benefits without the high, they would be more tolerant of more uses for the drug.
What misconceptions?
James
Particle Man
04-08-2011, 07:34 PM
However, if this removes the stigmata
I think the real question here is why you'd put nail holes in weed to begin with...
I think the real question here is why you'd put nail holes in weed to begin with...
stigma...better? LOL oops
Particle Man
04-08-2011, 07:37 PM
stigma...better? LOL oops
:lol
What misconceptions?
James
addictiveness
effects it actually has
Hell, I knew one guy that claimed to have witnessed people overdosing and dying from it. :lol: This isn't in war room, so I can't go into that. Why fuck didn't I put this in war room? Damnit, I suck....
Here you go Avy I will edit myself....I am a fairy princess.
:lol:
Avatard
04-08-2011, 07:43 PM
Here you go Avy I will edit myself....I am a fairy princess.
:lol:
Your sexual orientation is none of my business.
:lmao:
Avatard
04-08-2011, 07:45 PM
I think the real question here is why you'd put nail holes in weed to begin with...
See, I didn't wanna touch that in OT. I know you can't even mention _____.
:scared:
Kaneman
04-08-2011, 10:40 PM
Oh, bullshit. I make beer. As long as I don't try and sell it, I can make up to 100 gallons a year. No Federals come by to check my house etc... Most people are lazy. They will let an authorized grower package it and buy it over the counter. Same principle.
Not true. It would take one friend among a group of 20 to throw a few seeds outdoors and make enough herb to supply all of said friends for free...all year long. Brewing beer is harder and more involved than throwing some seeds out and watering, especially when you consider the return on effort.
Legalized weed = free or very, very cheap weed. As much of an advocate for legalization as I am, it will not improve the economy. The second it becomes completely legal it will be worthless.
Avatard
04-08-2011, 10:48 PM
...To everyone but those who need it as medicine, and to us, it's priceless.
Sorry to get all dramatic, but I'm a big fan of being able to walk, and other than Naproxin, it's pretty much all I got.
:shrug:
OneSickPsycho
04-09-2011, 08:37 AM
Not true. It would take one friend among a group of 20 to throw a few seeds outdoors and make enough herb to supply all of said friends for free...all year long. Brewing beer is harder and more involved than throwing some seeds out and watering, especially when you consider the return on effort.
Legalized weed = free or very, very cheap weed. As much of an advocate for legalization as I am, it will not improve the economy. The second it becomes completely legal it will be worthless.
Sorta like all those people who grow their own tobacco...
Sorta like all those people who grow their own tobacco...
Tobacco is hard fucking work. Shit ain't no joke. Stoners wouldn't want to do the work required to grow a good tobacco crop, they are too fucking lazy for it.
Avatard
04-09-2011, 09:26 AM
Don't confuse him with facts.
Don't confuse him with facts.
I don't think many people have experience with tobacco. I never realized how much work goes into it, til I want to my wife's grandparents farm. They use to grow tobacco. Shit was a nightmare.
Avatard
04-09-2011, 09:55 AM
One thing about it, though, it's a fucking miracle plant.
The most genetically modified plant EVER, even more so than Tomatoes.
Awesome genetic manipulation potential, as plants go, from what I understand.
But yeah, a "wee" bit more complicated than growing a weed.
Kaneman
04-09-2011, 09:57 AM
Sorta like all those people who grow their own tobacco...
Nope, not at all like that actually. People who smoke tobacco frequently use an ounce a day. Even hardcore cannabis users are not likely to use more than an ounce in two weeks, as long as the cannabis is high quality.
Curing tobacco and making it worthy of smoking is also much harder and time consuming than it is with cannabis.
One thing about it, though, it's a fucking miracle plant.
The most genetically modified plant EVER, even more so than Tomatoes.
Awesome genetic manipulation potential, as plants go, from what I understand.
But yeah, a "wee" bit more complicated than growing a weed.
What's even cooler is that we've been able to accomplish all that under prohibition.
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